Jack Daniel pioneers American whiskey; Adolphus Busch creates an iconic beer; Buck Duke innovates the modern cigarette; and Julius Schmid skirts the law selling his new condoms.

One of the richest men in the world may lose his tobacco empire, while alcohol titans fight for their lives against the growing threat of Prohibition. New York City becomes ground zero in the battle to legalize contraception.

The invention of the luxury resort casino helps birth Sin City; a Harlem woman goes to war for what will become the state lottery system; an alluring magazine like no other is launched.

Killer, drug smuggler, folk hero, Houdini of jailhouse escapes--the legend of Joaquin "El Chapo" Guzman is well known. But now this two-hour documentary special reveals an unprecedented look at the man behind the myth and how his international drug cartel impacts us right here at home.